Titanium’s excellent mechanical and physical properties make it a popular structural material commonly used in industry. However, the high chemical activity of titanium at high temperature necessitates the use of high-quality shielding gas during the welding process. The study discussed in the article aimed to assess the effect of welding parameters on the structure and mechanical properties of 3 mm thick butt joints in titanium Grade 2 (3.7035) made by means of the electron beam welding method under vacuum conditions without using the filler metal (511). The verification of joint quality involved the performance of hardness measurements, tensile tests, bend tests as well as macro and microscopic metallographic examinations. The tests results revealed the obtainability of joints characterized by appropriate penetration depth and geometry as well as optimum mechanical properties.